Research and Development

 

Body Content Level 5 - Through our research and development (R&D) programs, we are pioneering new healthcare solutions in disease areas with high unmet medical need - Cholecystectomyboost

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Body Content - level 3

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Cholecystectomyboost

Body Content - level 3
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VMS in her words
  • Landscape
  • clinical efficacy
  • convenience

VMS in her words

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Cholecystectomyboost - Burden of VMS 

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Diagnosis

Find out more about the impacts that VMS have on women. Oestrogen and neurokinin B (NKB) modulate KNDy neurons in a delicate balance, contributing to body temperature regulation.

Oestrogen and neurokinin B (NKB) modulate KNDy neurons in a delicate balance, contributing to body temperature regulation. KNDy neurons are stimulated by NKB and inhibited by oestrogen.1,2,3

  • Padilla SL, Johnson CW, Barker FD, Patterson MA, Palmiter RD.
  • A neural circuit underlying the generation of hot flushes. Cell Rep 2018;24(2):271-7.
  • 1.Krajewski-Hall SJ, Blackmore EM, McMinn JR, Rance NE.
  • 2.Krajewski-Hall SJ, Blackmore EM, McMinn JR, Rance NE.
  • 3.Krajewski-Hall SJ, Blackmore EM, McMinn JR, Rance NE.